Chronic Kidney Disease

No urination for a full day, severe swelling with trouble breathing, or confusion that’s new? Call 911 or go to the ER.
Call 911

Chronic kidney disease means your kidneys need support — not that they’ve stopped

Most CKD progresses slowly, and the right medications and diet choices can meaningfully slow that progression. Many people manage CKD for years without ever needing dialysis.

Blood pressure control is one of the most protective things you can do for your kidneys. The medications that lower blood pressure often protect kidney function too — taking them consistently matters even when you feel fine.

Some over-the-counter medications are worth avoiding

Common pain relievers like ibuprofen and naproxen (NSAIDs) can stress kidneys further. Check with your care team before taking any new over-the-counter medication or supplement.

Talk to your pharmacist

Time to check in on your kidney health?

4 quick questions. Nothing here is saved or stored — this stays in your browser.

1. New or increased swelling in your legs, ankles, or around your eyes?

Yes
No

2. Unusually foamy urine, or noticeably less urine than normal?

Yes
No

3. More fatigue or trouble concentrating than usual?

Yes
No

4. Has it been more than 6 months since your last kidney function blood test?

Yes
No

This is a general check-in, not a personal determination or diagnosis. Your nephrologist decides what’s right for you.

Medication options

For context, not a recommendation — your nephrologist will help choose what fits your situation.

Medication class What it does When it’s used
ACE inhibitors / ARBs Lower blood pressure and directly protect kidneys First-line for many CKD patients, especially with diabetes or protein in urine
SGLT2 inhibitors Originally diabetes drugs; now strongly recommended for kidney protection Increasingly recommended for many CKD patients
Diuretics (“water pills”) Help manage fluid and blood pressure Often used together with ACE/ARB
Potassium binders Lower high potassium when CKD makes that hard to manage Advanced CKD with high potassium
ESAs Treat anemia caused by advanced CKD Advanced CKD with low hemoglobin
About medication information here

The information here describes how a class of medications generally works and what to discuss with your provider or pharmacist. It is not a prescription, a recommendation of a specific drug or dose, or instructions to start, stop, or change any medication. Decisions about medications belong to you and your prescribing clinician.

Building your care team

Primary care provider
Manages most early CKD; coordinates overall care
Nephrologist
Kidney specialist; typically involved from Stage 3 onward
Renal dietitian
Specialized, high-impact nutrition guidance for kidney-aware eating
Your pharmacist
Kidney-aware medication dosing — a fast, easy first call
Transplant coordinator
When transplant is being considered or in progress
Diabetes educator
When diabetes is also present
Just had a hospital stay related to your kidneys? Being proactive about your follow-up is one of the most effective things you can do. Our Recovery Support hub walks through the full 30-day plan.
Also managing diabetes, high blood pressure, or cardiovascular disease? They’re closely connected to CKD, and managing them together protects your kidneys most effectively.

Ready to find care?

Search for a nephrologist or renal dietitian near you.

Find care near me

SynquUp is a patient-directed navigation and education platform. SynquUp is not a healthcare provider. The information here does not diagnose, treat, or replace care from your doctor, nurse, pharmacist, or other licensed clinician. SynquUp does not make clinical decisions for you. If something is wrong now, call 911 or go to the nearest emergency department. If you are thinking about harming yourself or someone else, call or text 988.

No urination / severe symptoms: Call 911
Emergency: 911
Mental health crisis: Call or text 988
Crisis Text Line: Text HOME to 741741

This page reflects general educational information, not an assessment of your specific condition. Always follow the plan given by your own care team.